ABCbiolab
SKU:ABCB08270
GR (Acetyl Lys494) Rabbit Polyclonal Antibody
GR (Acetyl Lys494) Rabbit Polyclonal Antibody
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Ab type
Primary antibody
Background
alternative products:At least 4 isoforms| Alpha (shown here)| Alpha-B| Beta and Beta-B| are produced by alternative initiation at Met-1 and Met-27. The existence of isoform Alpha and isoform Alpha-B has been proved by mutagenesis. As the sequence environment of the 2 potential ATG initiator codons is the same for the other altrnatively spliced isoforms| alternative initiation of translation could also occur on these transcripts. Additional isoforms seem to exist|disease:Defects in NR3C1 are a cause of glucocorticoid resistance
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
Synthesized peptide derived from human GR (Acetyl Lys494)
Storage Stability
-20°C for 1 year
Concentration
1 mg/ml
MolecularWeight_Da
85470
synonyms
GR ;Acetyl Lys494; Glucocorticoid receptor; GR; Nuclear receptor subfamily 3 group C member 1
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