GPX4 Antibody

Size

100ug

Clone Number

Aliases

Glutathione peroxidase 4 antibody; GPX 4 antibody; GPX-4 antibody; GPX4 antibody; GPX4_HUMAN antibody; GSHPx-4 antibody; MCSP antibody; mitochondrial antibody; PHGPx antibody; Phospholipid hydroperoxidase antibody; Phospholipid hydroperoxide glutathione peroxidase antibody; Phospholipid hydroperoxide glutathione peroxidase mitochondrial antibody; snGPx antibody; snPHGPx antibody; Sperm nucleus glutathione peroxidase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P36969

Immunogen

Recombinant Human Phospholipid hydroperoxide glutathione peroxidase, mitochondrial protein (74-197AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage. Essential for maturation and survival of photoreceptor cells. Plays a role in a primary T cell response to viral and parasitic infection by protecting T cells from ferroptosis, a cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species, and by supporting T cell expansion.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

GPX4

Research Areas

Cancer; Metabolism; Signal transduction