GPR68 Antibody

Size

100ul

Clone Number

Aliases

G protein coupled receptor 68 antibody; G-protein coupled receptor 68 antibody; GPR 12A antibody; GPR 68 antibody; GPR12A antibody; Gpr68 antibody; MGC111379 antibody; MGC156983 antibody; OGR 1 antibody; OGR-1 antibody; OGR1 antibody; OGR1_HUMAN antibody; Ovarian cancer G protein coupled receptor 1 antibody; Ovarian cancer G-protein coupled receptor 1 antibody; Sphingosylphosphorylcholine receptor antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15743

Immunogen

Recombinant Human Ovarian cancer G-protein coupled receptor 1 protein (276-365AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

GPR68

Research Areas

Signal transduction