GPR41 Polyclonal Antibody

Ab type

Primary antibody

Background

Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5-trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human FFAR3. AA range:11-60

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

38649

synonyms

FFAR3; GPR41; Free fatty acid receptor 3; G-protein coupled receptor 41