GPR143 Polyclonal Antibody

Ab type

Primary antibody

Background

GPR143 encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in GPR143 cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human GPR143. AA range:151-200

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

43878

synonyms

GPR143; OA1; G-protein coupled receptor 143; Ocular albinism type 1 protein