GP6 Antibody

Size

100ug

Clone Number

Aliases

Glycoprotein 6 antibody; Glycoprotein VI antibody; GP6 antibody; GPIV antibody; GPVI antibody; GPVI_HUMAN antibody; MGC138168 antibody; Platelet collagen receptor antibody; Platelet glycoprotein VI antibody; Platelet glycoprotein VI precursor antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9HCN6

Immunogen

Recombinant Human Platelet glycoprotein VI protein (115-265AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500

Background

Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

GP6

Research Areas

Cardiovascular