GMNN Antibody

Size

100ul

Clone Number

8H8

Aliases

Geminin, GMNN

Immunogen Species

Homo sapiens (Human)

UniProt ID

O75496

Immunogen

A synthesized peptide derived from human Geminin

Raised in

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:20-1:200

Background

Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.

Clonality

Monoclonal

Isotype

Rabbit IgG

Purification Method

Affinity-chromatography

Conjugate

Non-conjugated

Buffer

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

GMNN

Research Areas

Epigenetics and Nuclear Signaling; Cancer