GlyRBeta Polyclonal Antibody

Ab type

Primary antibody

Background

GLRB encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human GLRB. AA range:211-260

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

56122

synonyms

GLRB; Glycine receptor subunit beta; Glycine receptor 58 kDa subunit