GLIS3 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells| the thyroid| eye| liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human GLIS3

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

85250

synonyms

GLIS3