GIT1 Antibody

Size

100ug

Clone Number

Aliases

ARF GAP GIT1 antibody; ARF GTPase activating protein GIT1 antibody; ARF GTPase-activating protein GIT1 antibody; CAT 1 antibody; CAT-1 antibody; CaT1 antibody; Cool associated and tyrosine phosphorylated protein 1 antibody; Cool-associated and tyrosine-phosphorylated protein 1 antibody; G protein coupled receptor kinase interacting ArfGAP 1 antibody; G protein coupled receptor kinase interactor 1 antibody; G protein-coupled receptor kinase-interactor 1 antibody; GIT1 antibody; GIT1_HUMAN antibody; GRK interacting protein 1 antibody; GRK-interacting protein 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y2X7

Immunogen

Recombinant Human ARF GTPase-activating protein GIT1 protein (470-642AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis; the function may involve SDCCAG3 and PTPN13 (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

GIT1

Research Areas

Signal transduction