GIPR Polyclonal Antibody

Ab type

Primary antibody

Background

GIPR encodes Gastric inhibitory polypeptide receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking GIPR exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in GIPR thus may contribute to the pathogenesis of diabetes.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human GIPR. AA range:93-142

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

53157

synonyms

GIPR; Gastric inhibitory polypeptide receptor; GIP-R; Glucose-dependent insulinotropic polypeptide receptor