Gfer Antibody

Size

100ug

Clone Number

Aliases

Gfer antibody; AlrFAD-linked sulfhydryl oxidase ALR antibody; EC 1.8.3.2 antibody; Augmenter of liver regeneration antibody

Immunogen Species

Rattus norvegicus (Rat)

UniProt ID

Q63042

Immunogen

Recombinant Rat FAD-linked sulfhydryl oxidase ALR protein (1-198AA)

Raised in

Rabbit

Species Reactivity

Rat

Tested Applications

ELISA

Background

FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. May have a function in liver regeneration and spermatogenesis.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

Gfer

Research Areas

Cell biology; Signal transduction