gelE Antibody

Size

100ug

Clone Number

Aliases

gelE antibody; EF_1818Gelatinase antibody; EC 3.4.24.30 antibody; Coccolysin antibody

Immunogen Species

Enterococcus faecalis

UniProt ID

Q833V7

Immunogen

Recombinant Enterococcus faecalis Gelatinase protein (193-510AA)

Raised in

Rabbit

Species Reactivity

Enterococcus faecalis

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Metalloprotease capable of the hydrolysis of insoluble hydrophobic substrates. Hydrolyzes azocoll and gelatin and, at a lower rate, soluble and insoluble collagens. Does not cleave short synthetic peptides. Preferentially hydrolyzes the 24-Phe-|-Phe-25 bond in the insulin B-chain, followed by the 5-His-|-Leu-6 bond. Inactivates endothelin-1, primarily by cleavage of the 5-Ser-|-Leu-6 and 16-His-|-Leu-17 bonds. Hydrolyzes the alpha chain of C3 to generate a C3b-like protein. Inhibits complement-mediated hemolysis and opsinization of bacteria. Hydrolyzes the insect antimicrobial peptide cecropin. Decreases the length of E.faecalis chains via the activation of autolysin. Degrades polymerized fibrin.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

gelE

Research Areas

Others