GDF15 Monoclonal Antibody

Size

100ug

Clone Number

5E1A5

Aliases

Growth/differentiation factor 15, GDF-15, MIC1, PDF, PLAB, PTGFB

Immunogen Species

Human

UniProt ID

Q99988

Immunogen

Recombinant GDF15 Protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA,IHC;Recommended dilution:IHC:1:50-1:500

Background

Growth differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes.[1] GDF15 is also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB.[2] GDF15 mRNA is most abundant in the liver, with lower levels seen in some other tissues. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung.

Clonality

Monoclonal

Isotype

IgG2a

Purification Method

>95%,Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

GDF15

Research Areas

Cardiovascular?Cell biology;Signal transduction