GDF-9 Polyclonal Antibody

Ab type

Primary antibody

Background

GDF9 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Growth/differentiation factor 9 regulates ovarian function. Reduced expression of GDF9 may be associated with polycystic ovary syndrome and mutations in this gene may be more common in mothers of dizygotic twins.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human GDF-9. AA range:273-322

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

51444

synonyms

GDF9; Growth/differentiation factor 9; GDF-9