GCS-Beta-2 Polyclonal Antibody

Ab type

Primary antibody

Background

Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human GCS-beta-2. AA range:53-102

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

70368

synonyms

GUCY1B2; Guanylate cyclase soluble subunit beta-2; GCS-beta-2