GBP5 Polyclonal Antibody

Ab type

Primary antibody

Background

GBP5 (Guanylate Binding Protein 5) is a Protein Coding gene. Diseases associated with GBP5 include chronic active epstein-barr virus infection. Among its related pathways are Immune System and Interferon gamma signaling. GO annotations related to this gene include identical protein binding and GTPase activity. An important paralog of this gene is GBP7. s an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed: 22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed: 20180847).

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human GBP5.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

66617

synonyms

GBP5; Guanylate-binding protein 5; GBP-TA antigen; GTP-binding protein 5; GBP-5; Guanine nucleotide-binding protein 5