GATA-4 Polyclonal Antibody

Ab type

Primary antibody

Background

GATA4 encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. Transcription factor GATA-4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in GATA4 have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human GATA4. AA range:271-320

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

44627

synonyms

GATA4; Transcription factor GATA-4; GATA-binding factor 4