GAN Antibody

Size

100ul

Clone Number

Aliases

FLJ38059 antibody; GAN (gene name) antibody; GAN antibody; GAN_HUMAN antibody; GAN1 (gene name) antibody; Gigaxonin antibody; Kelch-like protein 16 antibody; KLHL16 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9H2C0

Immunogen

Recombinant Human Gigaxonin protein (1-240AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

GAN

Research Areas

Neuroscience; Signal transduction