G6PC2 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate| the terminal step in gluconeogenic and glycogenolytic pathways| allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity| but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described| but their biological validity has not been determined.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human G6PC2

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

G6PC2; Glucose-6-phosphatase 2; G-6-Pase 2; G6Pase 2; EC 3.1.3.9; Islet-specific glucose-6-phosphatase catalytic subunit-related protein