G3BP1 Antibody

Size

100ul

Clone Number

Aliases

ATP dependent DNA helicase VIII antibody; ATP-dependent DNA helicase VIII antibody; G3BP antibody; G3BP stress granule assembly factor 1 antibody; G3BP-1 antibody; G3bp1 antibody; G3BP1_HUMAN antibody; GAP binding protein antibody; GAP SH3 domain binding protein 1 antibody; GAP SH3 domain-binding protein 1 antibody; GTPase activating protein (SH3 domain) binding protein 1 antibody; hDH VIII antibody; Human DNA helicase VIII antibody; MGC111040 antibody; Ras GTPase activating protein binding protein 1 antibody; Ras GTPase activating protein SH3 domain binding protein antibody; Ras GTPase-activating protein-binding protein 1 antibody; RasGAP associated endoribonuclease G3BP antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q13283

Immunogen

Recombinant Human Ras GTPase-activating protein-binding protein 1 protein (227-466AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background

May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3\\\'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3\\\' tail or hanging tails at both 5\\\'- and 3\\\'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5\\\' to 3\\\' direction along the bound single-stranded DNA.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

G3BP1

Research Areas

Epigenetics and Nuclear Signaling