G-CSFR Polyclonal Antibody

Ab type

Primary antibody

Background

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC encodes Glutamate--cysteine ligase catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at GCLC have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human G-CSFR.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

72766

synonyms

CSF3R; GCSFR; Granulocyte colony-stimulating factor receptor; G-CSF receptor; G-CSF-R; CD antigen CD114