1
/
of
1
Feiyuebio
SKU:FY-IG0449-1
50/100
50/100
Regular price
$0.00 USD
Regular price
Sale price
$0.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
Name: Cleaved PARP Mouse Monoclonal Antibody(Mix-mA™)
Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:2,000-5,000 IHC 1:200-500
Specificity: Antibody can detect endogenous pro and active PARP proteins.
Alternative Names: PARP-1,Poly(ADP ribose) polymerase 1,sPARP1,ADPRT1,ADP ribosyltransferase NAD(+)
Background: Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1,when these breaks are encountered during DNA replication,the replication fork stalls,and double-strand DNA (dsDNA) breaks accumulate.
Applications: WB,IHC
Species Cross-Reactivity: H
Molecular Weight: 116KD(Pro),89(Active)
Protein MW （KDa）: 116KD(Pro),89(Active)
SWISS: P09874
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0449
Title: 50/100
Size Raw: IgG1
Size List: ['1']
Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:2,000-5,000 IHC 1:200-500
Specificity: Antibody can detect endogenous pro and active PARP proteins.
Alternative Names: PARP-1,Poly(ADP ribose) polymerase 1,sPARP1,ADPRT1,ADP ribosyltransferase NAD(+)
Background: Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1,when these breaks are encountered during DNA replication,the replication fork stalls,and double-strand DNA (dsDNA) breaks accumulate.
Applications: WB,IHC
Species Cross-Reactivity: H
Molecular Weight: 116KD(Pro),89(Active)
Protein MW （KDa）: 116KD(Pro),89(Active)
SWISS: P09874
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0449
Title: 50/100
Size Raw: IgG1
Size List: ['1']
Share
