EGFR Mouse Monoclonal Antibody(M6)

Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:1,000-3,000 IHC 1:100-200 IF 1:100-200 IP 1:200
Specificity: Antibody can detect endogenous EGFR proteins.
Alternative Names: Epidermal growth factor receptor antibody,erbb 1 antibody,Receptor tyrosine protein kinase ErbB 1 antibody
Background: The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF,TGFA/TGF-alpha,amphiregulin,epigen/EPGN,BTC/betacellulin,epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades.
Applications: WB,IHC,IF,IP
Species Cross-Reactivity: H
Molecular Weight: 170KD
Isotype: IgG1
Protein MW （KDa）: 170KD
SWISS: P00533
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0446
Title: EGFR Mouse Monoclonal Antibody(M6)
Size List: ['50', '100']