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Feiyuebio
SKU:FY-IG0389-50
Claudin-2 Mouse Monoclonal Antibody（8H11）
Claudin-2 Mouse Monoclonal Antibody（8H11）
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Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:1,000-2,000 IHC 1:100-200
Specificity: Antibody can detect endogenous Claudin-2 proteins.
Alternative Names: Claudin2,CLDN2,SP82
Background: The claudin family is composed of 23 integral membrane proteins,and their expression,which varies among tissue types,may determine both the strength and properties of the epithelial barrier. Alteration in claudin protein expression pattern is associated with several types of cancer . Claudin-2 is expressed primarily in the proximal tubule of the normal mammalian kidney,where it regulates transepithelial ion (e.g.,Na+,Cl-) reabsorption . Increased expression of Claudin-2 has been reported in some cancer cell lines ,including A549 lung adenocarcinoma cells,where its nuclear distribution was positively associated with enhanced proliferation .
Applications: WB,IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 25KD
Isotype: IgG1
Protein MW （KDa）: 25KD
SWISS: P57739
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0389
Title: Claudin-2 Mouse Monoclonal Antibody（8H11）
Size List: ['50', '100']
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:1,000-2,000 IHC 1:100-200
Specificity: Antibody can detect endogenous Claudin-2 proteins.
Alternative Names: Claudin2,CLDN2,SP82
Background: The claudin family is composed of 23 integral membrane proteins,and their expression,which varies among tissue types,may determine both the strength and properties of the epithelial barrier. Alteration in claudin protein expression pattern is associated with several types of cancer . Claudin-2 is expressed primarily in the proximal tubule of the normal mammalian kidney,where it regulates transepithelial ion (e.g.,Na+,Cl-) reabsorption . Increased expression of Claudin-2 has been reported in some cancer cell lines ,including A549 lung adenocarcinoma cells,where its nuclear distribution was positively associated with enhanced proliferation .
Applications: WB,IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 25KD
Isotype: IgG1
Protein MW （KDa）: 25KD
SWISS: P57739
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0389
Title: Claudin-2 Mouse Monoclonal Antibody（8H11）
Size List: ['50', '100']
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