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Feiyuebio
SKU:FY-IG0386-1
50/100
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Name: NFkB p65 Mouse Monoclonal Antibody (14H2)
Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:1,000-3,000 IHC 1:200 IP 1:200
Specificity: Antibody can detect endogenous NFkB p65 proteins.
Alternative Names: nan
Background: NFkB p65 is ubiquitinated leading to its proteosomal degradation,which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP,enhancing transcriptional activity. NFkB p65 is also acetylated at K122,enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB,which coordinates various aspects of immune function required for resistance to infection.
Applications: WB,IHC,IP
Species Cross-Reactivity: H,M,R
Molecular Weight: 65KD
Protein MW （KDa）: 65KD
SWISS: Q04206
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0386
Title: 50/100
Size Raw: IgG1
Size List: ['1']
Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:1,000-3,000 IHC 1:200 IP 1:200
Specificity: Antibody can detect endogenous NFkB p65 proteins.
Alternative Names: nan
Background: NFkB p65 is ubiquitinated leading to its proteosomal degradation,which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP,enhancing transcriptional activity. NFkB p65 is also acetylated at K122,enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB,which coordinates various aspects of immune function required for resistance to infection.
Applications: WB,IHC,IP
Species Cross-Reactivity: H,M,R
Molecular Weight: 65KD
Protein MW （KDa）: 65KD
SWISS: Q04206
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0386
Title: 50/100
Size Raw: IgG1
Size List: ['1']
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