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Feiyuebio
SKU:FY-IG0300-100
COX2 Cyclooxygenase 2 Rabbit Polyclonal Antibody
COX2 Cyclooxygenase 2 Rabbit Polyclonal Antibody
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Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:1,000 IHC 1:100
Specificity: Antibody can detect endogenous COX2 proteins.
Alternative Names: nan
Background: Prostaglandin-endoperoxide synthase 2,also known as cyclooxygenase-2 or simply COX-2,is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2,which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs,but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered,but their precise roles are yet to be described.
Applications: WB,IHC
Species Cross-Reactivity: H
Molecular Weight: 70KD
Isotype: IgG1
Protein MW （KDa）: 70KD
SWISS: P35354
Source: Rabbit
Antigen: Synthetic Peptide
Category: Polyclonal
Catalog Number: FY-IG0300
Title: COX2 Cyclooxygenase 2 Rabbit Polyclonal Antibody
Size List: ['50', '100']
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:1,000 IHC 1:100
Specificity: Antibody can detect endogenous COX2 proteins.
Alternative Names: nan
Background: Prostaglandin-endoperoxide synthase 2,also known as cyclooxygenase-2 or simply COX-2,is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2,which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs,but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered,but their precise roles are yet to be described.
Applications: WB,IHC
Species Cross-Reactivity: H
Molecular Weight: 70KD
Isotype: IgG1
Protein MW （KDa）: 70KD
SWISS: P35354
Source: Rabbit
Antigen: Synthetic Peptide
Category: Polyclonal
Catalog Number: FY-IG0300
Title: COX2 Cyclooxygenase 2 Rabbit Polyclonal Antibody
Size List: ['50', '100']
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