COX1 Cyclooxygenase 1 Rabbit Polyclonal Antibody

Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:1,000 IHC 1:100
Specificity: Antibody can detect endogenous COX1 proteins.
Alternative Names: nan
Background: Cyclooxygenase-1 (COX-1),also known as prostaglandin G/H synthase 1,prostaglandin-endoperoxide synthase 1 or prostaglandin H2 synthase 1,is an enzyme that in humans is encoded by the PTGS1 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2,which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs,but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered,but their precise roles are yet to be described.
Applications: WB,IHC
Species Cross-Reactivity: H
Molecular Weight: 70KD
Isotype: IgG
Protein MW （KDa）: 70KD
SWISS: P23219
Source: Rabbit
Antigen: Synthetic Peptide
Category: Polyclonal
Catalog Number: FY-IG0299
Title: COX1 Cyclooxygenase 1 Rabbit Polyclonal Antibody
Size List: ['50', '100']