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Feiyuebio
SKU:FY-IG0131-100
CD21 Mouse Monoclonal Antibody (2C5)
CD21 Mouse Monoclonal Antibody (2C5)
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Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: IHC 1:200
Specificity: Antibody can detect endogenous CD21 proteins.
Alternative Names: nan
Background: CD21 also known as complement receptor 2 (CR2),C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation,sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.
Applications: IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 113KD
Isotype: IgG1
Protein MW (KDa): 113KD
SWISS: P20023
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0131
Title: CD21 Mouse Monoclonal Antibody (2C5)
Size List: ['50', '100']
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: IHC 1:200
Specificity: Antibody can detect endogenous CD21 proteins.
Alternative Names: nan
Background: CD21 also known as complement receptor 2 (CR2),C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation,sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.
Applications: IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 113KD
Isotype: IgG1
Protein MW (KDa): 113KD
SWISS: P20023
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0131
Title: CD21 Mouse Monoclonal Antibody (2C5)
Size List: ['50', '100']
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