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Feiyuebio
SKU:FY-IG0101-50
CD68 Mouse Monoclonal Antibody(12E2)
CD68 Mouse Monoclonal Antibody(12E2)
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Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: IHC 1:200-500
Specificity: Antibody can detect endogenous CD68 proteins.
Alternative Names: CD68 antigen antibody,Macrophage antigen CD68 (microsialin) antibody,GP110 antibody
Background: The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages,Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages,both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins,allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.
Applications: IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 37KD
Isotype: IgG1
Protein MW （KDa）: 37KD
SWISS: P34810
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0101
Title: CD68 Mouse Monoclonal Antibody(12E2)
Size List: ['50', '100']
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: IHC 1:200-500
Specificity: Antibody can detect endogenous CD68 proteins.
Alternative Names: CD68 antigen antibody,Macrophage antigen CD68 (microsialin) antibody,GP110 antibody
Background: The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages,Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages,both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins,allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.
Applications: IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 37KD
Isotype: IgG1
Protein MW （KDa）: 37KD
SWISS: P34810
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0101
Title: CD68 Mouse Monoclonal Antibody(12E2)
Size List: ['50', '100']
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