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SKU:FY-IG0100-1
50/100
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Name: COX2 Cyclooxygenase 2 Mouse Monoclonal Antibody(3D4)
Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: IHC 1:50-100
Specificity: Antibody can detect endogenous COX2 proteins.
Alternative Names: PTGS2 antibody, Prostaglandin H2 synthase 2 antibody, PGHS 2 antibody, Glucocorticoid-regulated inflammatory cyclooxygenase antibody
Background: Prostaglandin-endoperoxide synthase 2,also known as cyclooxygenase-2 or simply COX-2,is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2,which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs,but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered,but their precise roles are yet to be described.
Applications: IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 74KD
Protein MW （KDa）: 70KD
SWISS: P35354
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0100
Title: 50/100
Size Raw: IgG1
Size List: ['1']
Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: IHC 1:50-100
Specificity: Antibody can detect endogenous COX2 proteins.
Alternative Names: PTGS2 antibody, Prostaglandin H2 synthase 2 antibody, PGHS 2 antibody, Glucocorticoid-regulated inflammatory cyclooxygenase antibody
Background: Prostaglandin-endoperoxide synthase 2,also known as cyclooxygenase-2 or simply COX-2,is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2,which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs,but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered,but their precise roles are yet to be described.
Applications: IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 74KD
Protein MW （KDa）: 70KD
SWISS: P35354
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0100
Title: 50/100
Size Raw: IgG1
Size List: ['1']
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