Fusin Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts| hypogammaglobulinemia| infections| and myelokathexis) syndrome. Alternate transcriptional splice variants| encoding different isoforms| have been characterized.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CXCR4. AA range:300-349

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

39746

synonyms

C-X-C chemokine receptor type 4; CXCR4; C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; FB22; Fusin; HM89; LCR1; Leukocyte-derived seven transmembrane domain receptor; LESTR; NPYRL; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD antigen CD184