Frizzled-8 Polyclonal Antibody

Ab type

Primary antibody

Background

This intronless gene FZD8 (frizzled class receptor 8) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. FZD8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human FZD8. AA range:486-535

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

73300

synonyms

FZD8; Frizzled-8; Fz-8; hFz8