Frizzled-4 Polyclonal Antibody

Ab type

Primary antibody

Background

FZD3 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of Frizzled-3 is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. FZD3 is a susceptibility locus for schizophrenia.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthetic peptide from human protein at AA range: 11-60

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

76263

synonyms

Frizzled-4 (Fz-4) (hFz4) (FzE4) (CD antigen CD344)