Frizzled-4 Polyclonal Antibody

Ab type

Primary antibody

Background

FZD4 (frizzled class receptor 4) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human FZD4. AA range:131-180

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

59881

synonyms

FZD4; Frizzled-4; Fz-4; hFz4; FzE4; CD antigen CD344