FOXL2 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

Blepharophimosis antibody; Blepharophimosis epicanthus inversus and ptosis 1 antibody; Blepharophimosis epicanthus inversus and ptosis antibody; BPES 1 antibody; BPES antibody; BPES1 antibody; Epicanthus inversus and ptosis 1 antibody; Forkhead box L2 antibody; Forkhead box protein L2 antibody; Forkhead transcription factor FOXL2 antibody; FOX L2 antibody; FOXL 2 antibody; FOXL2 antibody; FOXL2_HUMAN antibody; PFRK antibody; PINTO antibody; PITUITARY FORKHEAD FACTOR antibody; POF 3 antibody; POF3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P58012

Immunogen

Recombinant Human Forkhead box protein L2 protein (116-216AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

FOXL2

Research Areas

Epigenetics and Nuclear Signaling