FOLR1 Antibody

Size

100ug

Clone Number

Aliases

adult antibody; Adult folate binding protein antibody; Adult folate-binding protein antibody; FBP antibody; Folate Binding Protein antibody; Folate Receptor 1 Adult antibody; Folate receptor 1 antibody; Folate Receptor 1 Precursor antibody; Folate receptor adult antibody; Folate receptor alpha antibody; Folate receptor antibody; FOLR antibody; FOLR1 antibody; FOLR1_HUMAN antibody; FR alpha antibody; FR-alpha antibody; FRalpha antibody; KB cells FBP antibody; MOV18 antibody; Ovarian cancer associated antigen antibody; Ovarian tumor associated antigen antibody; Ovarian tumor associated antigen MOv18 antibody; Ovarian tumor-associated antigen MOv18 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P15328

Immunogen

Recombinant Human Folate receptor alpha protein (25-234AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500

Background

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

FOLR1

Research Areas

Tags & Cell Markers