Fli-1 Polyclonal Antibody

Ab type

Primary antibody

Background

FLI1 encodes friend leukemia integration 1 transcription factor containing an ETS DNA-binding domain. FLI1 can undergo a t (11;22) (q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t (4;11) (q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human FLI1. AA range:291-340

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

50982

synonyms

FLI1; Friend leukemia integration 1 transcription factor; Proto-oncogene Fli-1; Transcription factor ERGB