FKBP3 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human protein . at AA range: 140-220

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Peptidyl-prolyl cis-trans isomerase FKBP3 ;PPIase FKBP3;EC 5.2.1.8;25 kDa FK506-binding protein;25 kDa FKBP;FKBP-25;FK506-binding protein 3;FKBP-3;Immunophilin FKBP25;Rapamycin-selecti