Fibulin-3 Polyclonal Antibody

Ab type

Primary antibody

Background

EFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the EGF containing fibulin like extracellular matrix protein 1 contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human EFEMP1. AA range:111-160

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

54641

synonyms

EFEMP1; FBLN3; FBNL; EGF-containing fibulin-like extracellular matrix protein 1; Extracellular protein S1-5; Fibrillin-like protein; Fibulin-3; FIBL-3