FGF-23 Polyclonal Antibody

Ab type

Primary antibody

Background

FGF23 (fibroblast growth factor 23) encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in FGF23 are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human FGF23. AA range:151-200

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

27954

synonyms

FGF23; HYPF; Fibroblast growth factor 23; FGF-23; Phosphatonin; Tumor-derived hypophosphatemia-inducing factor