FERMT3 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

Fermitin family homolog 3 antibody; Fermitin family member 3 antibody; FERMT3 antibody; Kind3 antibody; Kindlin 3 antibody; Kindlin-3 antibody; Kindlin3 antibody; MGC10966 antibody; MIG 2 antibody; MIG2 like protein antibody; MIG2-like protein antibody; MIG2B antibody; Unc 112 related protein 2 antibody; Unc-112-related protein 2 antibody; UNC112C antibody; URP2 antibody; URP2_HUMAN antibody; URP2SF antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q86UX7

Immunogen

Recombinant Human Fermitin family homolog 3 protein (388-503AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Plays a central role in cell adhesion in hematopoietic cells (PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234460). Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

FERMT3

Research Areas

Immunology; Signal transduction