FDPS Antibody

Size

100ug

Clone Number

Aliases

(2E antibody; (2E,6E) farnesyl diphosphate synthase antibody; 6E)-farnesyl diphosphate synthase antibody; Dimethylallyltranstransferase antibody; Farnesyl diphosphate synthase antibody; Farnesyl diphosphate synthetase antibody; Farnesyl pyrophosphate synthase antibody; Farnesyl pyrophosphate synthetase antibody; Fdps antibody; FPP synthase antibody; FPP synthetase antibody; FPPS antibody; FPPS_HUMAN antibody; FPS antibody; Geranyltranstransferase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P14324

Immunogen

Recombinant Human Farnesyl pyrophosphate synthase protein (1-419AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IP:1:200-1:2000

Background

Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

FDPS

Research Areas

Cancer; Cardiovascular; Metabolism; Signal transduction