ABCbiolab
SKU:ABCCS46401
FBXO4 Antibody
FBXO4 Antibody
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Size
100ul
Clone Number
Aliases
DKFZp547N213 antibody; F box only protein 4 antibody; F box protein 4 antibody; F box protein Fbx4 antibody; F-box only protein 4 antibody; FBX4 antibody; FBX4_HUMAN antibody; FBXO 4 antibody; FBXO4 antibody; FLJ10141 antibody
Immunogen Species
Homo sapiens (Human)
UniProt ID
Q9UKT5
Immunogen
Recombinant Human F-box only protein 4 protein (138-387AA)
Raised in
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IHC, IP; Recommended dilution: IHC:1:20-1:200, IP:1:200-1:2000
Background
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes ubiquitination of CCND1 and its subsequent proteasomal degradation. Recognizes TERF1 and promotes its ubiquitination together with UBE2D1.
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
FBXO4
Research Areas
Cell biology
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