FBXO4 Antibody

Size

100ul

Clone Number

Aliases

DKFZp547N213 antibody; F box only protein 4 antibody; F box protein 4 antibody; F box protein Fbx4 antibody; F-box only protein 4 antibody; FBX4 antibody; FBX4_HUMAN antibody; FBXO 4 antibody; FBXO4 antibody; FLJ10141 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UKT5

Immunogen

Recombinant Human F-box only protein 4 protein (138-387AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IP; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000

Background

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes ubiquitination of CCND1 and its subsequent proteasomal degradation. Recognizes TERF1 and promotes its ubiquitination together with UBE2D1.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

FBXO4

Research Areas

Cell biology