fbpC Antibody

Size

100ug

Clone Number

Aliases

fbpC antibody; mpt45 antibody; MT0137Diacylglycerol acyltransferase/mycolyltransferase Ag85C antibody; DGAT antibody; EC 2.3.1.122 antibody; EC 2.3.1.20 antibody; Acyl-CoA:diacylglycerol acyltransferase antibody; Antigen 85 complex C antibody; 85C antibody; Ag85C antibody; Fibronectin-binding protein C antibody; Fbps C antibody

Immunogen Species

Mycobacterium tuberculosis

UniProt ID

P9WQN8

Immunogen

Recombinant Mycobacterium tuberculosis Diacylglycerol acyltransferase/mycolyltransferase Ag85C protein (46-340AA)

Raised in

Rabbit

Species Reactivity

Mycobacterium tuberculosis

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

fbpC

Research Areas

Others