fbpB Antibody

Size

100ul

Clone Number

Aliases

fbpBDiacylglycerol acyltransferase/mycolyltransferase Ag85B antibody; DGAT antibody; EC 2.3.1.122 antibody; EC 2.3.1.20 antibody; 30 kDa extracellular protein antibody; Acyl-CoA:diacylglycerol acyltransferase antibody; Antigen 85 complex B antibody; 85B antibody; Ag85B antibody; Extracellular alpha-antigen antibody; Fibronectin-binding protein B antibody; Fbps B antibody

Immunogen Species

Mycobacterium kansasii

UniProt ID

P21160

Immunogen

Recombinant Mycobacterium kansasii Diacylglycerol acyltransferase/mycolyltransferase Ag85B protein (41-325AA)

Raised in

Rabbit

Species Reactivity

Mycobacterium kansasii

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

fbpB

Research Areas

N/A