FAN Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human FAN

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

100870

synonyms

FAN