FAM134B Antibody

Size

100ug

Clone Number

Aliases

F134B_HUMAN antibody; FAM134B antibody; family with sequence similarity 134 member B antibody; HSAN2B antibody; JK 1 antibody; JK1 antibody; Protein FAM134B antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9H6L5

Immunogen

Recombinant Human Reticulophagy receptor FAM134B protein (1-131AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RETREG1

Research Areas

Others