FADS1 Antibody

Size

100ug

Clone Number

Aliases

D5D antibody; Delta 5 desaturase antibody; Delta 5 fatty acid desaturase antibody; Delta(5) desaturase antibody; Delta(5) fatty acid desaturase antibody; Delta-5 desaturase antibody; Fads1 antibody; FADS1_HUMAN antibody; FADS6 antibody; FADSD5 antibody; Fatty acid desaturase 1 antibody; FLJ38956 antibody; Linoleoyl CoA desaturase (delta 6 desaturase) like 1 antibody; LLCDL1 antibody; TU12 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O60427

Immunogen

Recombinant Human Fatty acid desaturase 1 protein (1-121AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Isoform 2 does not exhibit any catalytic activity toward 20:3n-6, but it may enhance FADS2 activity (By similarity). Isoform 1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3), respectively.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

FADS1

Research Areas

Cancer; Cardiovascular; Tags & Cell Markers; Metabolism; Signal transduction